Benzodiazepine

Benzodiazepines are generally hypnotic or anxiolytic depressant drugs.

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NameCategoriesSummary
3-OH-PHENAZEPAMtentativeresearch chemicalbenzohabit formingdepressant The 3-OH analogue of Phenazepam, which cuts the half life down quite a bit. Psychoactive effects are mostly lead by its metabolites, rather than the drug itself.
Alprazolambenzohabit formingdepressant commonAn extremely common benzodiazepine better known as Xanax, frequently prescribed for the treatment of anxiety and panic disorders. Alprazolam is short-lasting and primarily anxiolytic, though also possesses hypnotic properties. At high doses amnesia and loss of inhibition are common. Do not mix with other depressants.
Bentazepambenzodepressant habit formingThienodiazepine that is an effective anxiolyric. Liver damage among other nasty things have been reported.
Bromazepambenzohabit formingdepressant A benzodiazepine drug with a medium-long duration, developed by Roche in the 1960s. Has primarily anxiolytic properties. May cause lowered inhibitions and amnesia in high doses.
Bromazolambenzoresearch chemicaltentativehabit formingA rather novel Benzodiazepine that is structurally quite close to Alprazolam.
Brotizolamdepressant benzohabit formingdepressant Benzodiazepine analogue which is sedating, hypnotic and anxiolytic. It is available as prescription medicine in much of Europe, and is an extremely potent drug active at only 80ug. May cause amnesia and lowered inhibitions in overdose. Danger of respiratory depression when combined with other depressants. Short half life.
Camazepambenzohabit formingtentativedepressant A benzodiazepine drug that is stronger in terms of anxiety relief than it is in terms of how hypnotic it is. It is a metabolite of Diazepam and has limited anticonvulsant properties.
Clobazambenzohabit formingdepressant A long acting half life benzo that focues on Anxiolytic and/or Anticonvulsant.
Clonazepambenzohabit formingdepressant commonA medium-length common prescription benzodiazepine, often used to treat panic attacks because of its relatively fast sublingual onset. Primarily anxiolytic, but also possessing of other benzo traits.
Clonazolambenzoresearch chemicalhabit formingdepressant commonA long lasting benzodiazepine with heavily hypnotic effects. The safety profile is not well established, and there have been reports that people taking it three days in a row have had a seizure. Most comparable to Triazolam, but with a much longer half-life.
Cloniprazepambenzodepressant habit formingtentativeProdrug for Clonazepam.
Clorazepatedepressant benzohabit formingdepressant Is a prodrug for Desmethyldiazepam which is responsible for most of the therapeutic effects. Has a long half life, with the addition of Desmethyldiazepam as the main metabolite, which makes it much longer.
Clotiazepambenzohabit formingtentativedepressant Is a thienodiazepine substance. It differs from most other benzodiazepines in which the benzene ring has been replaced by a thiophene ring.
Delorazepambenzohabit formingdepressant Also known as chlordesmethyldiazepam, this uncommon benzodiazepine compound is primarily used for treatment of anxiety and Alcohol withdrawal, due to its long half-life (60-140 hours). It is also the active metabolite of Diclazepam and Cloxazolam.
Deschloroetizolambenzoresearch chemicalhabit formingtentativedepressant A Thienodiazepine which is close to its parent compound, Etizolam, whilst being significantly weaker and longer lasting.
Desmethylflunitrazepamdepressant benzohabit formingresearch chemicalBenzodiazepine that is a metabolite of Flunitrazepam, and has been sold as a research chemical.
Diazepambenzohabit formingdepressant commonA very common and widely prescribed benzodiazepine with hypnotic and sedative qualities. The metre by which other benzodiazepines are compared. May cause amnesia and lowered inhibitions in excess. Has a relatively long half-life in comparison with other benzodiazepines.
Diclazepambenzohabit formingdepressant A benzodiazepine drug and analogue of Diazepam first synthesised by Leo Sternbach at Hoffman-LaRoche in 1960, it has become prominent as an RC benzodiazepine on the grey market in recent years, particularly with the decline in Etizolam availability. A sedative and hypnotic it is of intermediate to long half life with similar effects to Diazepam, though 10x more potent.
Estazolambenzohabit formingdepressant A rarely prescribed medium-duration prescription benzodiazepine. Mainly used as a hypnotic, it can cause amnesia and lowered inhibitions in excess.
Ethaqualonedepressant benzoresearch chemicalhabit formingdepressant Analogue of Methaqualone that was mostly marketed in France. Slightly weaker and shorter acting than the prior.
Etizolambenzoresearch chemicalhabit formingdepressant A thienodiazepine anxiolytic. Similar in action to benzodiazepine drugs. Relieves anxiety, causes sedation and mild euphoria. High doses can lead to losing memory of what happened while on the drug. Users often compulsively re-dose frequently leading to accidental blackouts. Can be found in pressed pharmaceutical pills from various countries, clandestine pill presses, or as a powder
Flualprazolambenzohabit formingtentativeFluornated Alprazolam that is very close if not equipotent to the parent compound.
Flubromazepambenzoresearch chemicalhabit formingdepressant A somewhat common benzodiazepine drug. Sedative, hypnotic and anxiolytic, this compound is an analogue of Phenazepam. First discovered in the 1960s it was never marketed as a licit drug, but has recently become available as an RC. Not to be confused with Flubromazolam.
Flubromazolambenzoresearch chemicalhabit formingdepressant A very potent benzodiazepine derivative that is related to Triazolam and Pyrazolam. Popular in the research chemical scene, it is a potent sedative, hypnotic and anxiolytic. Potential for amnesia and reduced inhibitions in higher dose. Not to be confused with Flubromazepam, which is much less potent.
Flunitrazepambenzohabit formingdepressant Known as Rohypnol or 'roofies,' this infamous drug has similar qualities to most other benzodiazepines; sedating with strong hypnotic effects. Despite being known as a 'date rape drug' has only been implicated in a small number of such crimes. Danger of respiratory depression in combination with other depressants. May cause amnesia and lowered inhibitions in overdose.
Flunitrazolambenzodepressant habit formingtentativeA very potent hypnotic Benzodiazepine. Triazolo version of Flunitrazepam.
Flurazepambenzohabit formingdepressant Benzodiazepine with an extremely long half life, between 40 and 250 hours. Mainly used for general anxiety disorder. Sedating, hypnotic, anxiolytic. Potential for amnesia and reduced inhibitions in overdose.
Flutazolambenzohabit formingdepressant A benzodiazepine derivative. It was invented in Japan, and has mainly stayed in that area. Similar potency to Diazepam, yet produces a more marked sedation and impaired coordination. Usually used as a treatment for Insomnia. A hypnotic and sedative which may cause amnesia and lowered inhibitions in high doses.
Flutoprazepambenzohabit formingdepressant A potent benzodiazepine that is roughly 4-5x the potency of Diazepam and has a longer duration, rarely seen outside of Japan. Sedative, hypnotic and anxiolytic. May cause amnesia and loss of inhibitions in excess. Do not mix with other depressants.
Halazepambenzohabit formingdepressant A less common prescription benzodiazepine and derivative of Nordazepam. Also known as Paxipam, it is no longer prescribed in the USA. Sedating, hypnotic and anxiolytic. High doses may induce amnesia and lowered inhibitions.
Libriumbenzohabit formingdepressant Chlordiazepoxide, a medium-acting benzodiazepine drug prescribed mostly for sleep purposes. Sedative and hypnotic, it may cause lowered inhibitions and amnesia in high doses.
Lorazepambenzohabit formingdepressant commonAn intermediate acting benzodiazepine commonly known as Ativan, commonly prescribed as an alternative to Xanax. Sedating, hypnotic and anxiolytic. Potential to induce amnesia and lowered inhibitions in overdose. Do not combine with other depressants.
Lormetazepambenzodepressant habit formingRelatively rare prescription benzodiazepine. Short acting with a short half life. Generally only seen in the Netherlands. Sedative, hypnotic and anxiolytic.
Meclonazepambenzohabit formingdepressant tentativeA benzodiazepine related to Clonazepam discovered by Hoffman-LaRoche in the 1960s. Potentially useful in treating schistosomiasis. Has been sold on the grey market as a recreational drug but has not seen widespread popularity.
Medazepamdepressant benzohabit formingBenzodiazepine derivative that has all of the classic benzodiazepine effects. Is a long-acting benzodiazepine drug (Half life of 36-200 hours) Is rarely prescribed in most countries. Is also a prodrug for Diazepam. Think of it as Desoxy-Diazepam if you'd like to.
Metizolambenzoresearch chemicaldepressant habit formingtentativeAlso known as desmethyletizolam, a thienodiazepine similar in effects and structure to Etizolam, but around half as potent and with around a 60% longer half-life. A sedative, and hypnotic, it may cause amnesia and lowered inhibitions in excess.
Midazolambenzohabit formingdepressant A common hypnotic, sedative and anxiolytic benzodiazepine. High doses may cause amnesia and loss of inhibitions. Unusually, it is water soluble, and commonly used as a premedication for sedation as the solubility makes it better for IV use than other benzodiazepines.
Nifoxipambenzoresearch chemicalhabit formingtentativedepressant An uncommon and relatively new RC benzodiazepine, and metabolite of the hypnotic benzodiazepine Flunitrazepam. Little information about the pharmacological properties of this drug exists. Likely to be a strong sedative and hypnotic.
Nimetazepambenzohabit formingdepressant A pharmaceutical benzodiazepine with hypnotic and sedative effects. Rarely seen in the West but reportedly very frequently abused in Malaysia.
Nitemazepambenzodepressant habit formingtentativeA new RC benzodiazepine based off the chemical structure of Nimetazepam. It is relatively new and not many experience reports exist on it. It is expected to feel similar to Temazepam.
Nitrazepambenzohabit formingdepressant Hypnotic Benzodiazepine, that is used for short term relief of anxiety and insomnia. It has a pronouced affect on respritory action.
Nitrazolambenzohabit formingdepressant tentativeHypnotic benzodiazepine that is the triazolo analogue of Nitrazepam and about 4x more potent compared to the parent compound. Also the dechlorinated derivative of Clonazolam with roughly 1/10 potency.
Norflurazepambenzodepressant tentativehabit formingBenzodiazepine analogue that is an active metabolite to many other benzodiazepines, such as Flurazepam, Flutoprazepam, and Midazolam.
Oxazepambenzodepressant habit formingA prescription benzodiazepine with intermediate duration and half life. A sedative and hypnotic which may cause lowered inhibitions and amnesia in higher doses.
Phenazepambenzoresearch chemicalhabit formingdepressant A very long acting, potent and subtle benzodiazepine. Infamous for the calamitous experiences it tends to produce in people dosing unknown amounts. Prescribed in certain countries for epilepsy and Alcohol withdrawal.
Pinazepambenzodepressant habit formingBenzodiazepine that is solely an anxiolytic drug that lacks the hypnotic and motor impairment that most benzodiazepines do. The main metabolite of this is Nordazepam and to a lesser effect Oxazepam, which is where it gets most of its effects
Prazepambenzodepressant habit formingBenzodiazepine dervative. Has all the normal benzodiazepine-like quality (Anxiolytic/anticonvulsant/sedative/Skeletal muscle relaxant) It is also a prodrug for Desmethyldiazepam which is responsible for most if not all of the effects of Prazepam.
Pyrazolambenzoresearch chemicalhabit formingdepressant RC benzodiazepine discovered by Hoffman-LaRoche in the 1970s. Came to the RC market in the early 2010s. At lower doses it is mainly an anxiolytic compound, yet at higher doses can be quite sedating, hypnotic, amnesic, and can cause loss of inhibitions. Structurally similar to Alprazolam, Bromazepam, and Triazolam. Is 12x as potent as Diazepam.
Quazepambenzodepressant habit formingBenzodiazepine derivate drug, noral is prescribed for short term treatment of insomnia, and sleep maintenance. its MOA is very similar to Ambien and Sonata and substitutes for those in animal studies.
Rilmazafonebenzohabit formingdepressant Unique to Japan, this drug, also known as Rhythmy, is a benzodiazepine pro-drug which while inactive itself, is metabolised into the active compound in-vivo. Soluble in water.
Temazepambenzohabit formingdepressant Temazepam's brand name is Restoril. It is a hypnotic benzodiazepine with effects similar to Clonazepam, frequently prescribed as a sleep aid. Some users report mild euphoria alongside the hypnotic effects.
Tetrazepambenzohabit formingdepressant A benzodiazepine that has most of the properties of more common benzodiazepines. Yet was taken off the market in 2013. Has been noted to be more euphoric than most others.
Triazolambenzohabit formingdepressant An uncommon and very short acting benzodiazepine. Sedating and hypnotic, and may induce amnesia and lowered inhibitions at high doses.
Zolazepambenzodepressant habit formingA substance that is structurally related to benzodiazepines. Is only used in Veterinary medicine. It is usually used in tandem with either the potent NMDA antagonist Tiletamine (at a 1:1 ratio) or with the α2 adrenergic receptor agonist Xylazine. Is roughly around four times the potency of Diazepam. Yet is water soluable.

Factsheets on 54 drugs