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Tramadol

Basic Information

Summary

A synthetic opioid analgesic, Tramadol is used to treat moderate pain and can be considered a medium-strength opioid. Tramadol also has the unusual effect of being a serotonin releasing agent and a serotonin reuptake inhibitor, and as a consequence should not be taken in excess due to the risk of serotonin syndrome. Risk of seizures above 300mg doses.

Opioid

Opioids are pain-killing depressants which may also cause euphoria.

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Habit-forming

These drugs pose a higher risk of causing habit forming behaviour, take particular care with the amount and frequency they are taken.

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Depressant

Depressants are drugs which reduce arousal and stimulation in the user, characterised by a depressing of mental and physical functions.

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Common

Common drugs are those which are well known and widely used among the drug community. This doesn't necessarily mean they are safe, but it usually comes with a longer relative history of use in humans with which to establish a safety profile.

Dose
Oral
Light50-100mg
Common100-250mg
Heavy250-400mg

NOTE: Tramadol has a ceiling dose, where recreational effects are not increased. Risk of seizure at doses over 350mg. Tramadol decreases the seizure threshold, use extreme caution. Dosing insufflated is ineffective.

Duration
All ROAs
Onset1 hours
Duration5-7 hours
After-effects1-12 hours
Effects
    Effectseuphoria, elevated mood, overall feeling of contentedness, itching, drowsiness, vomiting, urinary retention, nausea, constipation, risk of seizure above 300mg
    Avoidbenzos, alcohol, and other opiates
    BioavailabilityOral 68-72% | Rectal 77%
    Aliasestram
    See TripSit Wiki for more information about drug interactions

    Interactions

    Dangerous

    Unsafe

    Caution

    Low risk & Increased Effects

    Low risk & No Synergy

    References & Notes

    General